Product Overview
Dehydroglyasperin D | TMA0291 | TargetMol Chemicals
CAS: 517885-72-2
Smiles: COc1cc2OCC(=Cc2c(OC)c1CC=C(C)C)c1ccc(O)cc1O
Formula: C22H24O5
Pathway: Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||DNA Damage/DNA Repair|||GPCR/G Protein|||Immunology/Inflammation|||MAPK|||Neuroscience|||PI3K/Akt/mTOR signaling|||Stem Cells
Target: GSK-3|||p38 MAPK|||ROS|||Akt|||COX|||PI3K|||DNA/RNA Synthesis|||Prostaglandin Receptor|||JNK
Receptor: N/A
Bioactivity: Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction with phosphatidylinositol 3-kinase; it also mediates suppression of both COX-2 expression and the MLK3 signalling pathway through direct binding and inhibition of MLK3. Dehydroglyasperin D shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet oxygen radicals.
Molecular Weight: 368, 42
![[D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P](https://cdn11.bigcommerce.com/s-2kvb5rm600/images/stencil/500x659/products/55083/51739/TargetMol-768x384__12443.1665998863__68435.1666081067.png?c=1 "[D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P")
![[D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P acetate](https://cdn11.bigcommerce.com/s-2kvb5rm600/images/stencil/500x659/products/55084/51740/TargetMol-768x384__12443.1665998863__89409.1666081068.png?c=1 "[D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P acetate")
