Product Overview
Delpazolid | T4165 | TargetMol Chemicals
CAS: 1219707-39-7
Smiles: CN1CCN(C=N1)c1ccc(cc1F)N1C[C@H](CO)OC1=O
Formula: C14H17FN4O3
Pathway: Microbiology/Virology
Target: Antibacterial|||Antibiotic
Receptor: N/A
Bioactivity: Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.
Molecular Weight: 308, 313
