Product Overview
Derazantinib | TQ0228 | TargetMol Chemicals
CAS: 1234356-69-4
Smiles: COCCNCCc1cccc(Nc2ncc3C[C@@H](c4ccccc4F)c4ccccc4-c3n2)c1
Formula: C29H29FN4O
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: FGFR
Receptor: N/A
Bioactivity: Derazantinib (ARQ-087) is an ATP competitive tyrosine kinase inhibitor. It exhibits potent activity against FGFR1/FGFR2/FGFR3 chondrocytes (IC50s: 4.5 nM/1.8 nM/4.5 nM).
Molecular Weight: 468, 576