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Product Overview
[Des-His1, Glu9]-Glucagon amide | TP2033 | TargetMol Chemicals
CAS: 110084-95-2
Smiles:
Formula: C148H221N41O47S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes); displays no agonist activity. Enhances glucose-stimulated pancreatic insulin release in vitro. Blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis in vivo. Also blocks endogenous glucagon-induced hyperglycemia in streptozocin diabetic rats.
Molecular Weight: 3358, 68
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