Product Overview
Desmethyl Erlotinib hydrochloride | T6619 | TargetMol Chemicals
CAS: 183320-51-6
Smiles: Cl.COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCO
Formula: C21H22ClN3O4
Pathway: Angiogenesis|||JAK/STAT signaling|||Metabolism|||Tyrosine Kinase/Adaptors
Target: EGFR|||Drug Metabolite
Receptor: N/A
Bioactivity: OSI-420 (Desmethyl Erlotinib, CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells.
Molecular Weight: 415, 87
