Product Overview
Desmethyl-QCA276 | T18601 | TargetMol Chemicals
CAS: 2126819-55-2
Smiles: Cc1nnc2COCc3c(Cc4ccccc4)c(sc3-n12)C#Cc1cn[nH]c1
Formula: C21H17N5OS
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].
Molecular Weight: 387, 46
