Product Overview
Desmorpholinyl Navitoclax-NH-Me | T39910 | TargetMol Chemicals
CAS: 2365172-82-1
Smiles: CC(C)(CC1)CC(CN(CC2)CCN2c(cc2)ccc2C(NS(c(cc2)cc(S(C(F)(F)F)(=O)=O)c2N[C@H](CCNC)CSc2ccccc2)(=O)=O)=O)=C1c(cc1)ccc1Cl
Formula: C44H51ClF3N5O5S3
Pathway: Apoptosis
Target: BCL
Receptor: N/A
Bioactivity: Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC BCL-XL degrader XZ739 [1] [2] .
Molecular Weight: 918, 55