Product Overview
Dezapelisib | T27157 | TargetMol Chemicals
CAS: 1262440-25-4
Smiles: C[C@H](Nc1ncnc2[nH]cnc12)c1nc2scc(C)n2c(=O)c1-c1cccc(F)c1
Formula: C20H16FN7OS
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Dezapelisib is an orally bioavailable, selective inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinases (PI3K). INCB040093 prevents both the production of the second messenger phosphatidylinositol-3, 4, 5-trisphosphate (PIP3) and the activation of the PI3K/AKT kinase signaling pathway. This decreases proliferation and induces cell death in PI3K-overexpressing tumor cells.
Molecular Weight: 421, 45