Product Overview
Diazaborine | T27165 | TargetMol Chemicals
CAS: 22959-81-5
Smiles: 6-methyl-2-(propylsulfonyl)thieno[3, 2-d][1, 2, 3]diazaborinin-1(2H)-ol OB1N(S(=O)(CCC)=O)N=CC2=C1C=C(C)S2
Formula: C9H13BN2O3S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Diazaborine inhibits maturation of rRNAs for the large ribosomal subunit. Diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1. Diazaborine treatment causes, within minutes, a rapid redistribution of the protein from the nucleolus to the periphery of the nucleus, which provides a possible explanation for the effect of diazaborine on rRNA processing.
Molecular Weight: 272, 14