DL-Glyceraldehyde | T4918

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TMC-T4918
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Product Overview

DL-Glyceraldehyde | T4918 | TargetMol Chemicals

CAS: 56-82-6

Smiles: OCC(O)C=O

Formula: C3H6O3

Pathway: Endocrinology/Hormones|||Metabolism

Target: Reductase

Receptor: N/A

Bioactivity: Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, glyceraldehyde can be a cytotoxin and a mutagen. A cytotoxin is a compound that kills cells. A mutagen is a compound that causes mutations in DNA. Glyceraldehyde is a highly reactive compound that can modify and cross-link proteins. Glyceraldehyde-modified proteins appear to be cytotoxic, depress intracellular glutathione levels, and induce reactive oxygen species (ROS) production (PMID: 14981296 ). Glyceraldehyde has been shown to cause chromosome damage to human cells in culture and is mutagenic in the Ames bacterial test.

Molecular Weight: 90, 078

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