Product Overview
DL-threo-2-methylisocitrate sodium | T19291 | TargetMol Chemicals
CAS: T19291
Smiles: O[C@@](C)(C([O-])=O)[C@@]([H])(C([O-])=O)CC([O-])=O.O[C@](C)(C([O-])=O)[C@]([H])(C([O-])=O)CC([O-])=O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Formula: C14H14Na6O14
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1 (ICL1). Using Michaelis-Menten nonlinear least squares fitting, kcat value was 5.24 s-1, the Km of the purified recombinant ICL1 of threonine-D(s)L(s)-isocitrate (ICA) was 188 μM. The Km of DL-threo-2-methylisocitrate (MICA) is approximately four times higher at 718 μM, and the kcat is 1.25 s-1.
Molecular Weight: 544, 19
