Product Overview
DM1-PEG4-DBCO | T17832 | TargetMol Chemicals
CAS: T17832
Smiles: COC1=CC(C/C(C)=C/C=C/[C@@H](OC)[C@]2(O)NC(OC([C@@H](C)C(O3)[C@]3(C)[C@@H](OC([C@H](C)N(C)C(CCCOCCOCCOCCOCCNC(CCC(N4CC(C=CC=C5)=C5C#CC6=C4C=CC=C6)=O)=O)=O)=O)CC7=O)C2)=O)=CC(N7C)=C1Cl
Formula: C63H80ClN5O16
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: DM1-(PEG)4-DBCO is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.
Molecular Weight: 1198, 79
