Product Overview
DNS-8254 | T27195 | TargetMol Chemicals
CAS: 1821107-98-5
Smiles: [H][C@]1(CN(CC(F)(F)C1)C(=O)c1ccc(F)c(Br)c1)c1cc(C)nc2ncnn12
Formula: C18H15BrF3N5O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: DNS-8254 is a potent and selective Phosphodiesterase 2 (PDE2) inhibitor for the treatment of Memory Disorders (hPDE2a IC50 = 8 nM, Rat Cl-int = 25.6 uL/min/mg). DNS-8254 demonstrated significant memory enhancing effects in a rat model of novel object recognition.
Molecular Weight: 454, 251
