Product Overview
Dolutegravir sodium | T2329 | TargetMol Chemicals
CAS: 1051375-19-9
Smiles: [Na+].CC1CCOC2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c([O-])c3C(=O)N12
Formula: C20H18F2N3NaO5
Pathway: Microbiology/Virology|||Proteases/Proteasome
Target: HIV Protease
Receptor: N/A
Bioactivity: Dolutegravir sodium salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Molecular Weight: 441, 367
