Product Overview
Dolutegravir | T6198 | TargetMol Chemicals
CAS: 1051375-16-6
Smiles: C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12
Formula: C20H19F2N3O5
Pathway: Microbiology/Virology|||Proteases/Proteasome
Target: HIV Protease
Receptor: N/A
Bioactivity: Dolutegravir (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Molecular Weight: 419, 385
