Product Overview
Droxinostat | T6481 | TargetMol Chemicals
CAS: 99873-43-5
Smiles: Cc1cc(Cl)ccc1OCCCC(=O)NO
Formula: C11H14ClNO3
Pathway: Apoptosis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: Apoptosis|||HDAC
Receptor: N/A
Bioactivity: Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
Molecular Weight: 243, 69
