DS-7423 | T36083

DS-7423 | T36083 | TargetMol Chemicals

CAS: 1222104-37-1

Smiles: N/A

Formula: C22H27F3N10O2

Pathway: PI3K/Akt/mTOR signaling

Target: PI3K|||mTOR

Receptor: N/A

Bioactivity: DS-7423 is a small-molecule dual inhibitor of phosphatidylinositol-3-kinase (PI3K) and mammalian target of rapamycin (mTOR). Although DS-7423 potently inhibits PI3Kα (IC50 = 15.6 nM) and mTOR (IC50 = 34.9 nM), it also inhibits other isoforms of class I PI3K (IC50 values: PI3Kβ = 1, 143 nM; PI3Kγ = 249 nM; PI3Kδ = 262 nM).

Molecular Weight: 520, 51