Product Overview
DS-7423 | T36083 | TargetMol Chemicals
CAS: 1222104-37-1
Smiles: N/A
Formula: C22H27F3N10O2
Pathway: PI3K/Akt/mTOR signaling
Target: PI3K|||mTOR
Receptor: N/A
Bioactivity: DS-7423 is a small-molecule dual inhibitor of phosphatidylinositol-3-kinase (PI3K) and mammalian target of rapamycin (mTOR). Although DS-7423 potently inhibits PI3Kα (IC50 = 15.6 nM) and mTOR (IC50 = 34.9 nM), it also inhibits other isoforms of class I PI3K (IC50 values: PI3Kβ = 1, 143 nM; PI3Kγ = 249 nM; PI3Kδ = 262 nM).
Molecular Weight: 520, 51
