Product Overview
DuP-697 | T15181 | TargetMol Chemicals
CAS: 88149-94-4
Smiles: CS(=O)(=O)c1ccc(cc1)-c1cc(Br)sc1-c1ccc(F)cc1
Formula: C17H12BrFO2S2
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: DuP-697 is an irreversible and orally active COX-2 inhibitor (IC50: 10 nM and 800 nM for human COX-2 and COX-1) with anti-inflammatory, anticancer, and antipyretic effects. DuP-697 shows antiproliferative (IC50: 42.8 nM), antiangiogenic and apoptotic effects on HT29 colorectal cancer cells.
Molecular Weight: 411, 3
