Product Overview
E-4177 | T27229 | TargetMol Chemicals
CAS: 135070-05-2
Smiles: Cc1ccnc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(nc12)C1CC1
Formula: C24H21N3O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: E-4177 is an angiotensin type 1 receptor antagonist. In rat adrenal cortex and liver, E4177 competitively inhibited the specific binding of 125I-[Sar1, Ile8]Ang II, with IC50 being (5.2 +/- 1.0) x 10(-8) M for the adrenal cortex and (1.2 +/- 0.3) x 10(-7) M for the liver.
Molecular Weight: 383, 451