Product Overview
E6446 dihydrochloride | T4068 | TargetMol Chemicals
CAS: 1345675-25-3
Smiles: Cl.Cl.C(COc1ccc(cc1)-c1nc2ccc(OCCCN3CCCC3)cc2o1)CN1CCCC1
Formula: C27H37Cl2N3O3
Pathway: Immunology/Inflammation
Target: TLR
Receptor: N/A
Bioactivity: E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM.
Molecular Weight: 522, 51
