Product Overview
Echistatin | TP2098 | TargetMol Chemicals
CAS: 154303-05-6
Smiles:
Formula: C217H341N71O74S9
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, αIIbβ3) receptors (IC50 = 30 nM) in vitro.
Molecular Weight: 5417, 1
