Product Overview
EF24 | T27242 | TargetMol Chemicals
CAS: 342808-40-6
Smiles: Cl.Fc1ccccc1\C=C1/CNC\C(=C/c2ccccc2F)C1=O
Formula: C19H16ClF2NO
Pathway: Apoptosis|||MAPK|||Proteases/Proteasome
Target: ERK|||MEK|||Caspase
Receptor: N/A
Bioactivity: EF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway.
Molecular Weight: 347, 79