Product Overview
ELR510444 | T2060 | TargetMol Chemicals
CAS: 1233948-35-0
Smiles: Cc1ccc(cc1)S(=O)(=O)Nc1cc(ccc1C)-c1ccc(s1)C#N
Formula: C19H16N2O2S2
Pathway: Apoptosis|||Cytoskeletal Signaling
Target: Apoptosis|||Microtubule Associated
Receptor: N/A
Bioactivity: ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in βIII-tubulin-overexpressing cell lines.
Molecular Weight: 368, 47
