Product Overview
Eltrombopag Olamine | T6825 | TargetMol Chemicals
CAS: 496775-62-3
Smiles: NCCO.NCCO.CC1=NN(C(=O)\C1=N/Nc1cccc(-c2cccc(c2)C(O)=O)c1O)c1ccc(C)c(C)c1
Formula: C29H36N6O6
Pathway: Proteases/Proteasome
Target: Thrombin
Receptor: N/A
Bioactivity: Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
Molecular Weight: 564, 643
