Product Overview
Endoxifen (Z-isomer) | T2280 | TargetMol Chemicals
CAS: 112093-28-4
Smiles: CC\C(=C(/c1ccc(O)cc1)c1ccc(OCCNC)cc1)c1ccccc1
Formula: C25H27NO2
Pathway: Angiogenesis|||Endocrinology/Hormones|||JAK/STAT signaling|||Membrane transporter/Ion channel|||Tyrosine Kinase/Adaptors
Target: Estrogen Receptor/ERR|||EGFR|||Potassium Channel|||Estrogen/progestogen Receptor|||HER
Receptor: N/A
Bioactivity: Endoxifen (EDX) is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptors that also inhibits aromatase activity.
Molecular Weight: 373, 496
