Product Overview
(-)-Epiafzelechin | TN1606 | TargetMol Chemicals
CAS: 24808-04-6
Smiles: O[C@H](C1)[C@@H](c(cc2)ccc2O)Oc2c1c(O)cc(O)c2
Formula: C15H14O5
Pathway: Immunology/Inflammation|||Neuroscience
Target: COX
Receptor: N/A
Bioactivity: (-)-Epiafzelechin exhibits significant anti-inflammatory activity on carrageenin-induced mouse paw edema, it exhibits a dose-dependent inhibition on the COX activity with an IC50 value of 15 microM, it exhibits about 3-fold weaker inhibitory potency on the enzyme activity than indomethacin as a positive control.
Molecular Weight: 274, 3