Product Overview
Ergosterol peroxide | TMA1743 | TargetMol Chemicals
CAS: 2061-64-5
Smiles: CC(C)[C@@H](C)\C=C\[C@@H](C)C1CC[C@@H]2[C@]1(C)CCC1[C@@]3(C)CC[C@H](O)C[C@@]33OO[C@@]21C=C3
Formula: C28H44O3
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||JAK/STAT signaling|||MAPK|||Microbiology/Virology|||PI3K/Akt/mTOR signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: ERK|||VEGFR|||p38 MAPK|||Wnt/beta-catenin|||Akt|||JAK|||CDK|||JNK|||STAT|||Antifection
Receptor: N/A
Bioactivity: Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Foxo3a activity by inhibiting pAKT and c-Myc and activating pro-apoptotic protein Puma and Bax to induce cancer cell death.Ergosterol peroxide can ameliorate TGF-β1-induced activation of kidney fibroblasts, it has the potential to be developed as a therapeutic agent to prevent renal fibrosis.
Molecular Weight: 428, 7
