Product Overview
ESI-05 | T15247 | TargetMol Chemicals
CAS: 5184-64-5
Smiles: Cc1ccc(cc1)S(=O)(=O)c1c(C)cc(C)cc1C
Formula: C16H18O2S
Pathway: GPCR/G Protein
Target: cAMP
Receptor: N/A
Bioactivity: ESI-05 is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.
Molecular Weight: 274, 38
