Product Overview
Estramustine | T20681 | TargetMol Chemicals
CAS: 2998-57-4
Smiles: C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC(N(CCCl)CCCl)=O)=C4)[C@@]3([H])CC2
Formula: C23H31Cl2NO3
Pathway: Cytoskeletal Signaling
Target: Microtubule Associated
Receptor: N/A
Bioactivity: Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken up by prostate cells and exerts antineoplastic effects by interfering with microtubule of dynamics and by reducing plasma levels of testosterone.
Molecular Weight: 440, 4
