Product Overview
Etoricoxib | T1574 | TargetMol Chemicals
CAS: 202409-33-4
Smiles: Cc1ccc(cn1)-c1ncc(Cl)cc1-c1ccc(cc1)S(C)(=O)=O
Formula: C18H15ClN2O2S
Pathway: Immunology/Inflammation|||Neuroscience
Target: COX
Receptor: N/A
Bioactivity: Etoricoxib is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
Molecular Weight: 358, 84