Product Overview
ETP-45658 | T25399 | TargetMol Chemicals
CAS: 1198357-79-7
Smiles: Cn1ncc2c(nc(nc12)-c1cccc(O)c1)N1CCOCC1
Formula: C16H17N5O2
Pathway: DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: DNA-PK|||PI3K|||mTOR
Receptor: N/A
Bioactivity: ETP 45658 is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively).
Molecular Weight: 311, 345
