Product Overview
Eudesmin | T3836 | TargetMol Chemicals
CAS: 526-06-7
Smiles: COc1ccc(cc1OC)[C@@H]1OC[C@@H]2[C@H]1CO[C@H]2c1ccc(OC)c(OC)c1
Formula: C22H26O6
Pathway: MAPK|||PI3K/Akt/mTOR signaling
Target: MAPK|||S6 Kinase
Receptor: N/A
Bioactivity: Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 microM (+)-eudesmin can induce neurite outgrowth and enhance nerve growth factor (NGF)-mediated neurite outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways.
Molecular Weight: 386, 444
