Product Overview
EZ-482 | T15265 | TargetMol Chemicals
CAS: 1016456-76-0
Smiles: Cn1nc(CC(=O)Nc2cc(ccc2O)S(=O)(=O)Nc2cccc(Cl)c2)c2ccccc2c1=O
Formula: C23H19ClN4O5S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: EZ-482 is a novel ligand of apolipoprotein (apoE). EZ-482 binds to apoE4 by a unique N-terminal allosteric effect and it also binds to sites on apoE in the C-terminal domain (Kds: 5-10 μM for apoE3 and apoE4).
Molecular Weight: 498, 94
