Product Overview
Facinicline hydrochloride | T28531 | TargetMol Chemicals
CAS: 677305-02-1
Smiles: Cl.O=C(N[C@@H]1CN2CCC1CC2)c1n[nH]c2ccccc12
Formula: C15H19ClN4O
Pathway: GPCR/G Protein|||Neuroscience
Target: 5-HT Receptor|||AChR
Receptor: N/A
Bioactivity: Facinicline hydrochloride is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimotor gating in rodents.
Molecular Weight: 306, 79
