Product Overview
Fedratinib | T1995 | TargetMol Chemicals
CAS: 936091-26-8
Smiles: Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C
Formula: C27H36N6O3S
Pathway: Angiogenesis|||Apoptosis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||FLT|||c-RET|||JAK
Receptor: N/A
Bioactivity: Fedratinib (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.
Molecular Weight: 524, 68
