Product Overview
Fenebrutinib HCl | TQ0242L | TargetMol Chemicals
CAS: 2128304-54-9
Smiles: Cl.C[C@H]1CN(CCN1c1ccc(Nc2cc(cn(C)c2=O)-c2ccnc(N3CCn4c5CC(C)(C)Cc5cc4C3=O)c2CO)nc1)C1COC1
Formula: C37H45ClN8O4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Fenebrutinib is orally available inhibitor of Bruton's tyrosine kinase (BTK) with antineoplastic activity. Upon administration, GDC-0853 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways, leading to the inhibition of the growth of malignant B-cells that overexpress BTK.
Molecular Weight: 701, 27
