Product Overview
Fengabine | T27310 | TargetMol Chemicals
CAS: 80018-06-0
Smiles: CCCC\N=C(\c1ccccc1Cl)c1cc(Cl)ccc1O
Formula: C17H17Cl2NO
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Fengabine is GABA receptor agonist. Its antidepressant effects are reversed by GABAA receptor antagonists like bicuculline and it has hence been labeled as GABAergic; however, it does not actually bind to GABA receptors, nor does it inhibit GABA-T. In clinical trials, fengabine's efficacy was comparable to that of the tricyclic antidepressants, but with a more rapid onset of action and much less side effects. Notably, fengabine lacks any sedative effects.
Molecular Weight: 322, 23