Product Overview
Fenobam | T15275 | TargetMol Chemicals
CAS: 57653-26-6
Smiles: CN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1
Formula: C11H11ClN4O2
Pathway: Neuroscience
Target: GluR
Receptor: N/A
Bioactivity: Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and non-competitive mGluR5 antagonist acting at an allosteric modulatory site (Kd values are 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively).
Molecular Weight: 266, 69
