Product Overview
Filgotinib | T1929 | TargetMol Chemicals
CAS: 1206161-97-8
Smiles: O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1
Formula: C21H23N5O3S
Pathway: Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: Tyrosine Kinases|||JAK
Receptor: N/A
Bioactivity: GLPG0634(filgotinib) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.
Molecular Weight: 425, 51
