Product Overview
Fipronil | T2196 | TargetMol Chemicals
CAS: 120068-37-3
Smiles: Nc1c(c(nn1-c1c(Cl)cc(cc1Cl)C(F)(F)F)C#N)S(=O)C(F)(F)F
Formula: C12H4Cl2F6N4OS
Pathway: Membrane transporter/Ion channel|||Metabolism|||Microbiology/Virology|||Neuroscience
Target: P450|||GluCls|||GABA Receptor
Receptor: N/A
Bioactivity: Fipronil is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels, resulting in central nervous system toxicity. This causes hyperexcitation of contaminated insects' nerves and muscles. Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also because GluCl channels do not exist in mammals.
Molecular Weight: 437, 14
