Product Overview
FK706 | T15285 | TargetMol Chemicals
CAS: 144055-55-0
Smiles: CC(C)[C@H](NC(=O)c1ccc(cc1)C(=O)NCC(=O)O[Na])C(=O)N1CCC[C@H]1C(=O)NC(C(C)C)C(=O)C(F)(F)F
Formula: C26H32F3N4NaO7
Pathway: Proteases/Proteasome
Target: Serine Protease
Receptor: N/A
Bioactivity: FK706 is a slow-binding and competitive human neutrophil elastase inhibitor (IC50: 83 nM; Ki: 4.2 nM). FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase (IC50s: 22 nM and 100 nM, respectively). FK706 has an anti-inflammatory effect.
Molecular Weight: 592, 548