Flindokalner | T15286

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€193.00 - €2,617.00
SKU:
TMC-T15286
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Product Overview

Flindokalner | T15286 | TargetMol Chemicals

CAS: 187523-35-9

Smiles: COc1ccc(Cl)cc1[C@]1(F)C(=O)Nc2cc(ccc12)C(F)(F)F

Formula: C16H10ClF4NO2

Pathway: Membrane transporter/Ion channel

Target: Potassium Channel

Receptor: N/A

Bioactivity: Flindokalner is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner displays a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM) and acts as a negative modulator of GABAA receptors and it also shows anxiolytic efficacy in vivo.

Molecular Weight: 359, 7

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