Product Overview
Forodesine | T15337 | TargetMol Chemicals
CAS: 209799-67-7
Smiles: OC[C@H]1N[C@H]([C@H](O)[C@@H]1O)c1c[nH]c2c1nc[nH]c2=O
Formula: C11H14N4O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine is an orally active inhibitor of purine nucleoside phosphorylase (IC50s: 0.48 to 1.57 nM for human, mouse, rat, monkey, and dog PNP). It could induce apoptosis in leukemic cells by increasing the dGTP levels.
Molecular Weight: 266, 257