Product Overview
Fosifloxuridine nafalbenamide | T33762 | TargetMol Chemicals
CAS: 1332837-31-6
Smiles: C[C@H](N[P](O)(=O)(OC[C@H]1O[C@@H](n2ccc(N)nc2=O)C(F)(F)[C@@H]1O)c1cccc2ccccc12)C(=O)OCc1ccccc1
Formula: C29H30F2N4O8P
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Target: DNA/RNA Synthesis
Receptor: N/A
Bioactivity: NUC-3373 (Fosifloxuridine nafalbenamide), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher concentrations of FUDR-MP in patients' cells.
Molecular Weight: 631, 55