Product Overview
Fostamatinib | T6115 | TargetMol Chemicals
CAS: 901119-35-5
Smiles: COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)N(COP(O)(O)=O)c4n3)n2)cc(OC)c1OC
Formula: C23H26FN6O9P
Pathway: Angiogenesis|||GPCR/G Protein|||Membrane transporter/Ion channel|||Neuroscience|||Tyrosine Kinase/Adaptors
Target: FLT|||Syk|||Monoamine Transporter|||Adenosine Receptor
Receptor: N/A
Bioactivity: Fostamatinib(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.
Molecular Weight: 580, 466