Product Overview
FRAX597 | T6014 | TargetMol Chemicals
CAS: 1286739-19-2
Smiles: CCn1c2nc(Nc3ccc(cc3)N3CCN(C)CC3)ncc2cc(-c2ccc(cc2Cl)-c2cncs2)c1=O
Formula: C29H28ClN7OS
Pathway: Cytoskeletal Signaling
Target: PAK
Receptor: N/A
Bioactivity: FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM).
Molecular Weight: 558, 1