Product Overview
FTI-277 hydrochloride | T2700 | TargetMol Chemicals
CAS: 180977-34-8
Smiles: Cl.COC(=O)[C@H](CCSC)NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c1ccccc1
Formula: C22H30ClN3O3S2
Pathway: Apoptosis|||GPCR/G Protein|||MAPK|||Metabolism
Target: Apoptosis|||Transferase|||Ras
Receptor: N/A
Bioactivity: FTI 277 hydrochloride is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than the closely related GGTase I.
Molecular Weight: 484, 07
