Product Overview
FTIDC | T3483 | TargetMol Chemicals
CAS: 873551-53-2
Smiles: CC(C)N(C)C(=O)N1CCC(=CC1)c1nnn(c1C)-c1cccnc1F
Formula: C18H23FN6O
Pathway: Neuroscience
Target: GluR
Receptor: N/A
Bioactivity: FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibition of FTIDC for mGluR1 receptors is shown to be in noncompetitive manner and displays IC50 values of 5.8 and 3.1 nM for human and mouse mGluR1 expressed in CHO cells respectively.
Molecular Weight: 358, 421