Product Overview
Fumaric acid | T3763 | TargetMol Chemicals
CAS: 110-17-8
Smiles: OC(=O)\C=C\C(O)=O
Formula: C4H4O4
Pathway: Metabolism
Target: Endogenous Metabolite
Receptor: N/A
Bioactivity: Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or an endogenous, cancer-causing metabolite. High levels of this organic acid can be found in tumors or biofluids surrounding tumors. Its oncogenic action appears due to its ability to inhibit prolyl hydroxylase-containing enzymes.
Molecular Weight: 116, 072
