G-744 | T15365

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TMC-T15365
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Product Overview

G-744 | T15365 | TargetMol Chemicals

CAS: 1346669-54-2

Smiles: Cn1cc(cc(Nc2ccncn2)c1=O)-c1cccc(N2CCc3c4CC(C)(C)Cc4sc3C2=O)c1CO

Formula: C29H29N5O3S

Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors

Target: BTK

Receptor: N/A

Bioactivity: G-744 is a selective and orally active inhibitor of Btk (IC50: 2 nM). G-744 is well-tolerated, metabolically stable. It also has an efficacious to treat arthritis.

Molecular Weight: 527, 64

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